Attenuated total reflection-Fourier transform infrared spectroscopic imaging of pharmaceuticals in microfluidic devices
نویسندگان
چکیده
منابع مشابه
Attenuated total reflection Fourier transform infrared spectra of faceted diamonds.
Attenuated total reflection Fourier transform infrared (ATR FT-IR) spectroscopy has been employed for characterization of faceted diamonds. ATR spectra of round brilliant cut natural diamonds of approximately 0.1 ct were observed with excellent spectral quality. The mirror-flat spectrum of the table facet enables a good contact to the ATR crystal with a minimal applied pressure. The observed AT...
متن کاملChemical visualization of individual chondrocytes in articular cartilage by attenuated-total-reflection Fourier Transform Infrared Microimaging
Fourier transform infrared imaging (FTIRI) and the attenuated total reflection Fourier transform infrared microimaging (ATR-FTIRM) were used to study the chemical and structural distributions of cellular components surrounding individual chondrocytes in canine humeral cartilage, at 6.25µm pixel resolution in FTIRI and 1.56µm pixel resolution in ATR-FTIRM. The chemical and structural distributio...
متن کاملSingle-pass attenuated total reflection Fourier transform infrared spectroscopy for the prediction of protein secondary structure.
Principal component regression (PCR) was applied to a spectral library of proteins in H2O solution acquired by single-pass attenuated total reflectance (ATR) Fourier transform infrared (FT-IR) spectroscopy. PCR was used to predict the secondary structure content, principally alpha-helical and the beta-sheet content, of proteins within a spectral library. Quantitation of protein secondary struct...
متن کاملAttenuated total reflection Fourier transform infrared spectroscopy for on-chip monitoring of solute concentrations.
We report a cost-efficient Attenuated Total Reflection Fourier Transform Infrared Spectroscopy (ATR-FTIR) method for monitoring concentrations of solutes in solutions flowing through microfluidic channels. The method allows rapid acquisition of spectra and enables chemical characterisation and concentration measurements that are independent of the flow rate of liquids. The method enables indepe...
متن کاملPH-dependent coordination of metal-lisinopril complex investigated by attenuated total reflection/Fourier transform infrared spectroscopy.
In order to simulate the in vivo binding behavior of angiotensin-converting enzyme (ACE) inhibitors to the zinc-containing active center of ACE, the in vitro interaction between lisinopril and zinc or nickel ions was investigated in aqueous solutions of different pH by using attenuated total reflection (ATR)/Fourier transform infrared (FT-IR) spectroscopy with second-derivative IR spectral anal...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biomicrofluidics
سال: 2016
ISSN: 1932-1058
DOI: 10.1063/1.4946867